Lehrstuhl für
Organische Chemie I
Lichtenbergstraße 4
85747 Garching

Tel  +89.289.13330
Fax +89.289.13315

Aktuelle Publikationen
Enantioselective Intermolecular [2 + 2] Photocycloaddition Reactions of 2(1H)-Quinolones Induced by Visible Light Irradiation
J. Am. Chem. Soc. 2016, 138, 7808-7811
Recent Advances in the Synthesis of Cyclobutanes by Olefin [2 + 2] Photocycloaddition Reactions
Chem. Rev. 2016, in Press
Enantioselective Visible-Light-Induced Radical-Addition Reactions to 3-Alkylidene Indolin-2-ones
Chem. Eur. J. 2016, 22, 6519-6523
Enantioselective [4+4] photodimerization of anthracene-2,6-dicarboxylic acid mediated by a C2- symmetric chiral template
Chem. Commun. 2016, 52, 1032-1035
Peter Lemmen

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Peter Lemmen

apl. Prof. Dr.

URL: Synthese und Evaluierung borhaltiger Tumorsucher für die Bor-Neutronen-Einfang-Therapie von Tumoren

70. L.O.A. Manguro, P. Lemmen,P. Hao, K.-C. Wong, Journal of Asian Natural Products Research 2012, 14, 987-1001.
'Triterpene saponins of Maesa lanceolata stem wood'

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69. M. Oelgemoeller, R. Frank, P. Lemmen, D. Lenoir, J. Lex, Y. Inoue, Tetrahedron 2012, 68, 4048-4056.
'Synthesis, structural characterization and photoisomerization of cyclic stilbenes'

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68. L.O.A.Manguro, P. Lemmen, P. Hao, Records of Natural Products 2011, 5, 147-157.
'Iridoid Glycosides from Underground Parts of Ajuga remota '
67. S.A. Opiyo, L.O.A.Manguro, P. Okinda-Owuor, E.M. Ateka, P. Lemmen, Phytochemistry Lett. 2011, 4, 161-165.
'7 alpha-Acetylugandensolide and antimicrobial properties of Warburgia ugandensis extracts and isolates against sweet potato pathogens '

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66. L.O.A. Manguro, S.A. Opiyo, E. Herdtweck, P. Lemmen, Can. J. Chem. 2009, 87, 1173-1179.
'Triterpenes of Commiphora holtziana oleo-gum resin'

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65. L.O.A. Manguro, J.A. Ogur, D.M. Okora, S.O. Wagai, P. Lemmen, Journal of Asian Natural Products Research 2007, 9, 617-629.
'Further flavonol and iridoid glycosides from Ajuga remota aerial parts'

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64. L.O.A. Manguro, P. Lemmen, Nat. Prod. Res. 2007, 21, 56-68.
'Phenolics of Moringra oleifera leaves '

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63. P. Lemmen, E. Fontain, J. Bauer, Angew. Chem. Int. Ed. Engl. 2006, 45, 193-193.
'Ivar K. Ugi (1930-2005): Multi-component reactions, computer and phosphorus chemistry - Obituary'

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62. L.O.A. Manguro, S.O. Wagai, P. Lemmen, Phytochemistry 2006, 67, 830-837.
'Flavonol and iridoid glycosides of Ajuga remota aerial parts'

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61. L.O.A. Manguro, Lawrence Onyango, S.O. Okwiri, P. Lemmen, Phytochemistry 2006, 67, 2641-2650.
'Oleanane-type triterpenes of Embelia schimperi leaves '

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60. L.O.A. Manguro, I. Ugi, P. Lemmen, J. Chin. Chem. Soc. 2005, 52, 201-208.
'Flavonol glycosides from the leaves of Embelia keniensis '
59. L.O.A. Manguro, I. Ugi, P. Lemmen, Chem. Pharm. Bull. 2003, 51, 479-482.
'Further bisabolenes and dammarane triterpenes of Commiphora kua resin'
58. L.O.A. Manguro, I. Ugi, P. Lemmen, Chem. Pharm. Bull. 2003, 51, 483-486.
'Dammarane triterpenes of Commiphora confusa resin'
57. L.O.A. Manguro, LOA, I. Ugi, R. Hermann, P. Lemmen, Phytochemistry 2003, 63, 497-502.
'Flavonol and drimane-type sesquiterpene glycosides of Warburgia stuhlmannii leaves'

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56. J. Buchner, A. Skerra, P. Lemmen, Nachr. Chem. 2003, 51, 932-935.
'Not just the Abitur transcript - On the admission of students at TU Munich'
55. L.O.A. Manguro, I. Ugi, P. Lemmen, R. Hermann, Phytochemistry 2003, 64, 891-896.
'Flavonol glycosides of Warburgia ugandensis leaves '

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54. M. Oelgemoller, B. Brem, R. Frank, S. Schneider, D. Lenoir, N. Hertkorn, Y. Origane, P. Lemmen, J. Lex, Y. Inoue, J. chem. Soc., Perkin Trans. 2 2002, 1760-1771.
'Cyclic trans-stilbenes: synthesis, structural and spectroscopic characterization, photophysical and photochemical properties'

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53. D. Ernst, L. Rupp, R. Frank, W. Kuhnle, P. Lemmen, D. Lenoir, J. Schroeder, C. Grimm, T. Steinel, Z. Phys. Chem. 2002, 216, 555-574.
'Fluorescence excitation spectrum, lifetimes and photoisomerization of jet-cooled conformers of 1,1'-bi(benzocyclobutylidene)'

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52. L.O.A. Manguro, P. Lemmen, I. Ugi, W. Kraus, Natural Product Sciences 2002, 8, 77-82.
'Flavonol Glycosides of Maesa Lanceolata Leaves'
51. P. Lemmen, L. Weissfloch, T. Probst, P. Luppa, P.L. Micca, M. Miura, Frontiers in Neutron Capture Therapy; Kluwer Academic / Plenum Publishers: New York 2001, 1057-1061.
'Cremophor EL alters uptake, retention, distribution, and toxicity of the boron containing ether lipid rac-l-(9-o-carboranyl)nonyl-2-methyl-glycero-3-phosphocholine (B-Et-11-OMe)'
50. P. Lemmen, G. Kühne, L. Weissfloch, T. Probst, M. Molls, PSI Proceedings 01-01, Paul-Scherrer-Institut, Villingen, CH 2001, 88-91.
'Untersuchungen zur Verteilung borhaltiger Substanzen in tumortragenden Mäusen'
49. C. Chiappe, A. De Rubertis, P. Lemmen, D. Lenoir, J. Org. Chem. 2000, 65, 1273-1279.
'Steric strain and reactivity: Electrophilic bromination of trans-(1-Methyl-2-adamantylidene)-1-methyladamantane'

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48. R. Bianchini, C. Chiappe, G. Lo Moro, D. Lenoir, P. Lemmen, N. Goldberg, Chem. Eur. J. 1999, 5, 1570-1580.
'Spectroscopic and theoretical investigations of electrophilic bromination reactions of alkynes: The first evidence for π-complexes as reaction intermediates'

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47. Weissfloch, M. Bremer, P. Lemmen, T. Probst, M. Wagner, M. Peller, T. Auberger, R. Senekowitsch-Schmidtke, K. Tempel, M. Molls, Strahlenther Onkol 1999, 175 Suppl. 2, 118-120.
'New drugs for BNCT: An experimental approach'
46. L. Weissfloch, P. Lemmen, M. Wagner, T. Probst, H. Feldmann, T. Auberger, M. Molls, Progress in Radio-Oncology; Proceedings of the 6th International Meeting on Progress in Radio-Oncology ICRO/ÖGRO 6; Salzburg, Austria, May 13-17, 1998 1998, 57-64.
'BNCT: development and evaluation of new drugs'
45. D. Gabel et al., Cancer Research Supported under BIOMED I 1998, 24, 282-287.
'Clinical implementation of neutron capture therapy '
44. A.A. Semioshkin, S.G. Inyushin, L.V. Ermanson, P.V. Petrovskii, P. Lemmen, V.I. Bregadze, Russ. Chem. Bull. 1998, 47, 1985-1988.
'Interactions of carborane-containing electrophiles with triethyl phosphite. Synthesis of new carborane-containing phosphonates '

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43. P. Lemmen, L. Weissloch, H. Goerlitzer, D. Gabel, P. Olsson, O. Petterson, S. Teichmann, Advances in Neutron Capture Therapy: Proc. 7th Intern. Symp. on Neutron Capture Therapy for Cancer, Zürich, 4.-7. Sept. 1996 1997, 1132/2, 108-112.
'Synthesis of boron-containing ether lipids for boron neutron capture therapy'
42. M. Molls, M. Bremer, L. Weissfloch, T. Auberger, F.M. Wagner, et al. , Der neue deutsche Hochfluß-Forschungsreaktor FRM II; Jahrestagung Kerntechnik ´97; INFORUM Verlag: Bonn 1997, 30-41.
'Strahlentherapie mit Neutronen am Forschungsreaktor der Technischen Universität München'
41. A. Semioshkin, P. Lemmen, S. Inyushin, L. Ermanson , Advances in Boron Chemistry; The Royal Society of Chemistry: Cambridge 1997, 311-314.
'Alkyl carboranyl sulfonates as available synthons for carboranyl derivatives, especially for carborane-containing phosphonic acid esters. '
40. G. Bellucci, C. Chiappe, R. Bianchini, P. Lemmen, D. Lenoir, Tetrahedron 1997, 53, 785-790.
'Concentration dependence of the steric course of bromine addition to acenaphthylene. A product and kinetic study '

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39. R. Bianchini, C. Chiappe, D. Lenoir, P. Lemmen, R. Herges, J. Grunenberg, Angew. Chem. Int. Ed. Engl. 1997, 36, 1284-1287.
'Spectroscopic detection and theoretical studies of a 2:1 bromine-olefin π-complex'

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38. T.U. Probst, N.G. Berryman, P. Lemmen, L. Weissfloch, T. Auberger, D. Gabel, J. Carlsson, B. Larsson, J. .Anal. At. Spect. 1997, 12, 1115-1122.
'Comparison of inductively coupled plasma atomic emission spectrometry and inductively coupled plasma mass spectrometry with quantitative neutron capture radiography for the determination of boron in biological samples from cancer therapy'

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37. P. Lemmen, L. Weißfloch, T. Auberger, T. Probst, Cancer Neutron Capture Therapy - Proceedings of the 6th ISNCT; Plenum Press: New York 1996, 649-654.
'Uptake and distribution of the boron containing ether lipid B-Et-11-OMe in tumor bearing mice: a preliminary study.'
36. S. Teichmann, J.F. Crawford, D. Gabel, B. Larsson, P. Lemmen, et al. , PSI Annual Report 1995 Annex II <7i>(PSI Life Sciences and Institute for Medical Radiobiology) 1995, 98-100.
'Neutron capture radiography'
35. P. Lemmen, L. Weissfloch, T. Auberger, T. Probst, Anti-Cancer Drugs 1995, 6, 744-748.
'Uptake and distribution of the boron-containing ether lipid B-Et-11-OMe in tumor-bearing mice'

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34. P. Lindstrom, P. Olsson, J. Malmqvist, J. Pettersson, P. Lemmen, B. Werner, S. Sjoberg, A. Olin, J. Carlsson, Anti-Cancer Drugs 1994, 5, 43-52.
'New carborane based compounds for boron neutron capture therapy. Binding and toxicity of ANC-1, DAC-1, and B-Et-11-OMe in cultured human glioma and mouse melanoma cells'

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33. P. Lemmen, B. Werner, B. Streicher, Neutron Capture Therapy; Plenum Press: New York 1993, 297-300.
'Ether Lipids as potential Boron Carriers for Boron-Neutron-Capture-Therapy. Synthesis of rac-1-(9-o-Carboranyl)-nonyl-2-methyl-glycero-3-phosphocholine (B-Et-11-OMe)'
32. P. Lemmen, W. Richter, B. Werner, R. Karl, R. Stumpf, I. Ugi, Synthesis 1993, 1-10.
'Five-Membered Cyclic Phosphorylating Reagents and related Compounds'
31. I. Ugi, N. Bachmeier, M. Klein, P. Lemmen, A. Micossi, W. Richter, M. Strasser, R. Stumpf, B. Werner, Adv. Nat. Prod. Chem. 1992, 91-120.
'Cyclic Phosphates in Synthesis of Nucleotides, Phospholipids and related Compounds'
30. P. Lemmen, B. Werner, Chem. Phys. Lipids 1992, 62, 185-191.
'Synthesis of rac-1-(9-o-carboranyl)nonyl-2-methyl-glycero-3- phosphocholine (B-Et-11-OMe), a potential boron carrier for Boron Neutron Capture Therapy (BNCT)'

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29. I. Ugi, N. Bachmeier, R. Herrmann, P. Jacob, R. Karl, M. Klein, B. Landgraf, P. Lemmen, W. Richter, U. Verfürth, Phosphorus 1990, 51, 57-60.
'Synthesis and Reactivity of Five-Membered Cyclic Phosphorylating Reagents and other Auxiliaries for the Synthesis of Oligonucleotides'
28. P. Lemmen, K.M. Buchweitz, R. Stumpf, Chem. Phys. Lipids 1990, 53, 65-75.
'A synthesis of phospholipids using a phosphite-triester approach and uniformly cleavable β-halogenated protecting groups'

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27. R. Stumpf, P. Lemmen, Z. Naturforsch. 1990, 45B, 1729-1731.
'Synthesis of Phospholipids via Oxazaphospholanes'
26. R. Karl, P. Lemmen, I. Ugi, Synthesis 1989, 718-719.
'Synthesis of 3'-Isocyano-3'-deoxythymidine'
25. I. Ugi, P. Jacob, B. Landgraf, C. RUPP, P. Lemmen, U. Verfürth, Nucleosides and Nucleotides 1988, 7, 605-608.
'Phosphite Oxidation and the Preparation of five-membered cyclic Phosphorylating Reagents via the Phosphites'

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24. P. Lemmen, M. Baumgartner-Rupnik, Nucleosides and Nucleotides 1988, 7, 707-711.
'On the influence of the Nature of 2-N-protecting acyl groups on the stability of deoxyguanosine derivatives'

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23. I. Ugi, J. Achatz, M. Baumgartner-Rupnik, B. Danzer, C. Fleck, et al., Natural Products Chemistry III; Springer Verlag: Heidelberg 1988, 107-133.
'New reagents and methods for the synthesis of β-lactams, peptides and oligonucleotides'
22. C. Lemmen, K. Stuhler, P. Lemmen, G. Wolfram, Biol. Chem. Hoppe-Seyler 1988, 369, 1267-1273.
'Utilization of medium-chain triglycerides and octanoic acid by cultured human fibroblasts and lymphoblasts'

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21. P. Lemmen, R. Baumgartner, I. Ugi, F. Ramirez, Chemica Scripta 1988, 28, 451-464.
'The deformation of the phosphorane skeleton as evidence for reorganisation pathways'
20. P. Lemmen, R. Karl, I. Ugi, N. Balgobin, J. Chattopadhyaya, Z. Naturforsch. 1987, 42c, 442-445.
'Bausteine für Oligonukleotid-Synthesen mit einheitlich fragmentierbaren β-halogenierten Schutzgruppen'
19. P. Lemmen, I. Ugi, Chemica Scripta 1987, 27, 297-301.
'The Chiroptic Properties of the Diastereomeric 1,1'-Dimethyl-2,2'-spiro-biindanes -- a Comparative Study'
18. I. Ugi, H. Aigner, G. Glahsl, R. Herges, G. Hering, et al., Natural Product Chemistry; Springer Verlag: Heidelberg 1986, 457-484.
'New Reagents and Methods for the Synthesis of Peptides, β-Lactams and Oligonucleotides'
17. I. Ugi, J. Bauer, E. Fontain, J. Götz, G. Hering, P. Jacob, B. LandgrafF, R. Karl, P. Lemmen, R. Schneiderwind-Stöcklein, R. Schwarz, P. Sluka, N. Balgobin, J. Chattopadhyaya, T. Pathak, X.X. Zhou, Chemica Scripta 1986, 26, 205-215.
'New Phosphorylating Reagents and Protective Group Techniques for Oligonucleotide Synthesis, as well as Computer Assistance in the Design of Reagents'
16. P. Lemmen, Nucleosides and Nucleotides 1985, 4, 247-248.
'Trichloro-tert.-butyl-cyclic-enediol-phosphate (TCB-CEP), Proposed Reagent for the Syntheses of Oligonucleotides using the Triester Approach'

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15. J. Vogel, S. Schneider, F. Dörr, P. Lemmen, D. Lenoir, Chemical Physics 1984, 90, 387-398.
'Photophysics of cis- and trans-1-(1-Indanylidene)indane. Spectroscopic Evidence for Aggregation of the trans Isomer'

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14. P. Lemmen, D. Lenoir, Chem. Ber. 1984, 117, 2300-2313.
'Reduktive Kupplungsreaktionen aus der Reihe des 1-Indanons, 1-Tetralons und 9-Fluorenons; konformative Effekte in der Reihe der Indanylidenindane und Tetralinylidentetraline'

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13. V. Buss, L. Simon, P. Lemmen, J. Chem. Soc., chem. Commun. 1984, 1696-1698.
'Synthesis, Circular Dichroism, and Absolute Configuration of Two Chiral Indanylideneindans'

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12. I. Ugi, H. Aigner, M.L.V. Arnaez, H. Burghard, G. Glahsl, et al., Waters GmbH: Eschborn 1984, 1-39.
'Synthesen mit Derivaten von Nucleosiden, α-Aminosäuren, Peptiden und β-Lactamantibiotika als Anwendungsbeispiele für HPLC. Studium und Optimierung selektiver chemischer Reaktionen mittels HPLC'
11. P. Lemmen, Liebigs Ann. Chem. 1983, 668-677.
'Synthese und Bestimmung der absoluten Konfiguration des medialen(1R,1'S,2S)- und des distalen (S,S)-1,1'-Dimethyl- 2,2'-spirobiindans'
10. P. Lemmen, Chem. Ber. 1982, 1902-1910.
'Synthese und Bestimmung der absoluten Konfiguration des proximalen (S,S)-1,1'-Dimethyl-2,2'-spirobiindans'

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9. D. Lenoir, P. Lemmen, Chem. Ber. 1980, 3112-3119.
'Reaktion von 1-Indanonen mit niedrigwertigen Titanverbindungen. Sterischer Einfluß von Methylsubstituenten bei 1-(1-Indanyliden)indan und 9-(9-Fluorenyliden)fluoren'

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8. P. Lemmen, D. Lenoir, Fresenius Z. Anal. Chem. 1980, 304, 284-285.
'Kraftfeldrechnungen an Fluorenylidenfluorenen. Vergleich der berechneten Geometrie eines stark tordierten Olefins mit den Röntgenstrukturdaten'

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7. P. Lemmen, Tetrahedron Lett. 1979, 4461-4462.
'2,4-Dichlor-2-oxo-5-methyl-1,3,2-λ5-dioxaphospholen, ein cyclisches Enolphosphat von Milchsäurechlorid als neues Phosphorylierungsreagenz'
6. I. Ugi, J. Brandt, J. Friedrich, J. Gasteiger, C. Jochum, P. Lemmen, W. Schubert, Pure Appl. Chem. 1978, 50, 1303-1318.
'The Deductive Solution of Chemical Problems by Computer Programs on the Basis of a Mathematical Model of Chemistry'

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5. I. Ugi, P. Lemmen, F. Ramirez, Chem. Ber. 1976, 109, 3738-3739.
'Notiz über eine verbesserte Methode zur Darstellung von 5t-Acetyl-2r-methoxy-5c-methyl-2,4-dioxo-1,3,2-λ5-dioxaphospholan (cis-Methyl-CAP)'

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4. F. Ramirez, J.F. Marecek, I. Ugi, P. Lemmen, D. Marquarding, D., Phosphorus 1975, 5, 73-84.
'Phosphate and Oxyphosphorane Models for Adenosine-3',5'- cyclophosphate'
3. I. Ugi, F. Ramirez, E. von Hinrichs, P. Lemmen, J. Firl, J. Chem. Soc., chem. Commun. 1974, 979-980.
'Silyl Esters of a Fife-membered Cyclic Acyl Phosphate'
2. F. Ramirez, S.L. Glaser, P. Stern, I. Ugi, P. Lemmen, Tetrahedron 1973, 29, 3741-3752.
'Five Membered Cyclic Acyl Phosphates. New Class of Extremely Reactive Phosphorylating Agents'

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1. F. Ramirez, P. Stern, S.L. Glaser, I. Ugi,; P. Lemmen , Phosphorus 1973, 3, 165-173.
'Selective Phosphorylations of Primary Alcohols in the Presence of Unprotected Secondary Alcohols'